Core Markets

Life Sciences

Building Complex Labs and Facilities "Inside-Out"

DPR's experienced construction managers and engineers address all utility services and casework issues up front—building from an "inside-out" perspective—to ensure a timely and cost-efficient delivery of projects. From small, economical biology labs for start-up companies to complex biocontainment facilities for world-class life science corporations, DPR's range of proven expertise provides customers with a seasoned driver equipped in planning, coordinating, constructing and validating even the most technically challenging and complex laboratories and facilities.

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Technical Expertise

Experienced Research Laboratory Builders
We have created a standard checklist of items common to most laboratory facilities to help our customers arrive at the most practical, cost-effective design solutions. Having worked with most manufacturing equipment vendors, we have an accurate installation cost database. DPR can offer numerous options to be reviewed with technical and cost input available for casework, fume hoods, utility distribution, HVAC controls, process controls, and facility finishes.

Leaders in Construction of GMP Manufacturing Plants
DPR understands that technical competency and speed of project delivery are key elements in the successful construction of a GMP manufacturing plant or pilot facility. We have built out solid dosage, large-scale fermentation facilities, purification suites, fill and finish facilities, and numerous other facilities including diagnostics and device manufacturing. To support their requirements, we have developed a keen understanding of current and proposed FDA regulations and recognize the changing nature of those regulations.

Validation and Turnover Package Expertise
To successfully qualify a facility, it is essential that the qualification team have a detailed understanding of the regulatory requirements of the FDA. DPR understands FDA requirements and has developed a guideline manual to aid our engineers in preparing turnover packages. We work closely with regulatory and validation personnel to ensure thorough and accurate IQ/OQ documentation. DPR experts stay on top of industry trends through:

  • Attendance at PDA/FDA joint conferences to remain current on the status of regulatory matters
  • Participation in local chapters of ISPE and PDA, including participation in focus groups concerning construction qualification and turnover packages
  • Acquisition and distribution of the latest FDA regulations and industry publications
  • Review of the latest trends in the specification and cost of utility systems including WFI, clean steam, and air handling/filtration equipment

DPR understands that the quality we build into a facility will significantly affect validation time. To ensure customer success with validation, we help build in validation requirements and acceptance criteria during the design phase to avoid later confusion or design changes.

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Projects by Core Market

Projects by Office Location

I do not know of any other firm that offers anything comparable to DPR's Zero Defects Program. DPR not only advertises but really delivers as close as you can get to zero defects on its projects.